NMN Supplement Review

 

nicotinamide based nmn molecule

The quest for combating the effects of the aging process has spiked in recent years. Individuals are seeking ways not only to live a longer life but also have a more vibrant, youthful appearance. A significant amount of money is spent yearly on pills, powders, and creams to look younger. There is a specific molecule on the rise in the anti aging world that is worthy of attention. Nicotinamide mononucleotide, more commonly known as NMN, is taking on aging at the cellular level. It’s time to familiarize yourself with it, and the best NMN supplements available on the market today.

Sirtuin research has been in the news recently due to dr sinclair’s video and joe rogan interview. He discussed nicotinamide riboside and DNA repair in that interview. He is doing clinical trials for reversing aging in mice. At Harvard medical school clinical trials are underway for nicotinamide mononucleotide nmn precursors in humans. Vitamin B3 is one natural precursors to nicotinamide adenine dinucleotide very good for human health and cancer prevention other mitochondrial precursors for preventing cancer are being studied at Harvard university medical school.

Is NMN Better Than NAD ?

Two critical components are the backbone for anti aging effects. You need NMN to boost NAD+nicotinamide adenine dinucleotide, which is an enzyme that makes daily life possible. NAD+ levels decline as much as 50% as we age. With dropped NAD+ levels, a noticeable decline in our energy level is apparent as we become older, which decreases the bodies ability to make healthy cells. Think of your intracellular production like an assembly line. As one cell goes down, it is quickly replaced with another optimal one.  This process inhibits with age, so increasing your level of NMN has been found to fine-tune cellular production, and is found naturally in foods with Vitamin B3, such as whole wheat flour, avocados, or grapefruits. While including this anti aging supplement in the diet is beneficial, we will also take a look at the best organic supplements available. More specifically, you’ll understand the role they take in the health and beauty industry in 2019.

Alive By Nature

Alive By Nature has a mixture of NMN supplements, including pills in various counts and NMN powder. The pills chewable, yet the effectiveness of this NMN tablet is the ability to take it sublingually. It has a great taste that absorbs into the bloodstream. Instead of being digested, these tablets are more readily available for cells in the body. The product’s popularity is evident in the amount of testing done to ensure safety standards. Several studies with humans have been completed proving the safety and effectiveness of NMN delivery, with more research to be completed in the second half of 2019. Alive By Nature is a new company, but they are among leaders in NMN supplementation.

ProHealth aging supplement

This product is available as a lozenge form, with each one containing 150mg of NMN. It also comes in pills and NMN powder. Pro Health is trusted because they have been producing quality products for over a 30-year time span. The company believes in backing all their supplements with science-based research, which gives consumers confidence in their anti aging products. If you are searching for an NMN product with a quality reputation, it’s hard to go wrong with ProHealth  supplements.

MAAC 10

Each capsule contains 125 mg of NMN. While other health products benefits are with sublingual ingestion, MAAC 10 is superior in the digestive role. As a product that claims 99% pure NMN, MAAC 10 gets it absorbed in the stomach. This amount of pure powder means your cells can have the NAD+ in 10 minutes or less. Many reviews of MAAC 10 have consumers reported increased energy levels, more endurance for workout programs, and resolved skin problems.

RevGenegics Advanced NMN: Nicotinamide mononucleotide

RevGenegics is a relatively newer company being in business for only ten years. During that time, they received an A+ rating by the Better Business Bureau. Each capsule contains 25 mg of NMN but also has a 99% purity level like MAAC 10.  If you are looking to get a boost of energy and increased quality of life, this product may be for you.

Are There NMN supplements Alternatives? 

High Performance Nutrition: NAD+ Booster

Even the best NMN supplements may not be for you, so there are other options. This product improves cellular health, increases your energy, and sustains and increases NAD+ levels in the body. Also, a significant benefit of this product is the reported reviews from customers on how it decreases inflammation in their muscles. Increased levels of NAD+ can also increase one’s motility.

LIfe Extension NAD+ Cell Regenerator

Another natural alternative that promotes healthy cell function if you’re feeling weak and tired. Studies have been done with Life Extension that showed improved cognitive functioning. Each capsule contains 100 mg of Nicotinamide Riboside.

Study was published in the January 2019 journal Antioxidants & Redox Signaling

“Nicotinamide adenine dinucleotide (NAD+) is an essential pyridine nucleotide that serves as an essential cofactor and substrate for a number of critical cellular processes involved in oxidative phosphorylation and ATP production, DNA repair, epigenetically modulated gene expression, intracellular calcium signaling, and immunological functions. NAD+ depletion may occur in response to either excessive DNA damage due to free radical or ultraviolet attack, resulting in significant poly(ADP-ribose) polymerase (PARP) activation and a high turnover and subsequent depletion of NAD+, and/or chronic immune activation and inflammatory cytokine production resulting in accelerated CD38 activity and decline in NAD+ levels. Recent studies have shown that enhancing NAD+ levels can profoundly reduce oxidative cell damage in catabolic tissue, including the brain. ” Nady Braidy, at the Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales wrote, “Therefore, promotion of intracellular NAD+ anabolism represents a promising therapeutic strategy for age-associated degenerative diseases in general, and is essential to the effective realization of multiple benefits of healthy sirtuin activity. The kynurenine pathway represents the de novo NAD+ synthesis pathway in mammalian cells. NAD+ can also be produced by the NAD+ salvage pathway.”

“In this publication, we describe and discuss current insights regarding the efficiency and human health benefits of the NAD+ precursors, nicotinamide mononucleotide (NMN), nicotinic acid (NA), nicotinamide riboside (NR), and nicotinamide mononucleotide , in affecting NAD+ decline in degenerative disease states and physical aging. Study results obtained in recent years have shown that NAD+ can increase precursors to play important protective roles in several diseases including cancer. However, in some cases, these precursors may vary in their ability to enhance NAD+ synthesis via their location in the NAD+ metabolic pathway. Increased synthesis of NAD+ promotes protective cell responses, further demonstrating that NAD+ is a regulatory molecule associated with several biochemical pathways. In the next few years, we can increase refinement of personalized therapy for the use of NAD+ precursors and improved detection methodologies allowing the administration of specific NAD+ precursors in the context of patients’ NAD+ levels will lead to a better understanding of the therapeutic role of NAD+ precursors in human diseases.”

The Bottom Line On NMN Research

You might not have heard much about the best anti aging because the research behind it is somewhat new. Studies have found using natural cancer prevention to be generally safe, but more scientific study is on the way. In 2019, the desire to have a solid combatant for anti aging is more significant to consumers than ever. If you’re searching for quality alternative liver disease preventative products, consider the ones listed above.  There’s a reason why billions of dollars are spent every year to look and feel more youthful. While most people want quality research behind a product, cancer prevention will likely be a trend to stay because of the positive impact they’ve made in a short amount of time. In a generation that spends so much money on health and beauty items, these supplements may prove to be well worth the money

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